Sunpure-HS Series Chromatographic Packing Material
Sunpure-HS series is a premium silica gel chromatographic packing material featuring advanced sphere packing technique with excellent control over particle size and pore size distribution. It offers higher resolution, better stability under high pH, and higher mechanical strength, making it particularly suitable for the purification of polypeptide products including GLP-1 and its analogs.
Key Features and Advantages
- Uniform particle size distribution
- Advanced bonding technology support
- Lower column pressure with high column efficiency
- High-purity silica matrix
- Low metal surface density
- Excellent mechanical strength
Low Metal Residue
The minimized metal microstructure on the silica gel surface prevents changes in solute shape and retention characteristics, particularly important for sensitive compounds like 2,3-dimethylpyridine.
Reduced metal-catalyzed degradation
Improved peak symmetry
Enhanced compound recovery
More reproducible results
Highly De-activated Surface
When pH > 7, the deactivated surface minimizes peak shape deterioration for basic compounds like amitriptyline, with retention characteristics serving as indicators of chromatographic performance.
Product Specifications
Product Series |
Bonded Phase |
Particle Size (μm) |
Pore Size (Å) |
Item No. |
pH Range |
Sunpure-HS C8 |
C8 |
10 |
100 |
HS8102000-0 |
2-9 |
Sunpure-HS C18 |
C18 |
10 |
100 |
HS9102000-0 |
2-9 |
Sunpure-HS C8 Pro |
C8 |
10 |
100 |
HST102000-0 |
2-10 |
Sunpure-HS Silica |
Silica |
10 |
100 |
HSS102000-0 |
2-8 |
Application Methods
Method 1: Metal Content Analysis
Material: Sunpure-HS C18 10μm, 100Å
Mobile Phase: 1.0 C18,OH = 50%-50%
Sample: 2,3-dimethylpyridine
Flow Rate: 0.8mL/min
Detection: UV 254nm, 30°C
Method 2: Surface Activity Test
Material: Sunpure-HS C18 10μm, 100Å
Mobile Phase: 1.0 mM KH₂PO₄,OH=20%-80%
Sample: Amitriptyline test mix
Flow Rate: 1.0mL/min
Detection: UV 254nm, 30°C