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Oligopeptides Purification

Oligopeptides Purification Report

SUN-OLIGO-2025-08 August 2025

Sunpure introduces two innovative chromatographic materials specifically optimized for oligopeptide purification. The Sunpure-BS C18 Pro and Sunpure-BS AQ C18 demonstrate exceptional performance in separating complex oligopeptide mixtures with high purity and recovery rates.

Oligopeptide-5 Purification

Preparation Chromatogram

Purification Method

Column Sunpure-BS C18 Pro 8µm 120Å
Item Number BSE082000-2
Sample Oligopeptide-5 crude
Loading Capacity 1%
Flow Rate 3mL/min
Mobile Phase A: 0.1% TFA in water | B: 0.1% TFA in ACN

Purification Results

99.00%
Purity
90.02%
Recovery
1.00%
Max Single Impurity

Oligopeptide-10 Purification

Preparation Chromatogram

Purification Method

Column Sunpure-BS AQ C18 10µm 100Å
Item Number BSM102000-0
Sample Oligopeptide-10 crude
Loading Capacity 3%
Flow Rate 3mL/min
Mobile Phase A: 0.1% TFA in water | B: 0.1% TFA in ACN

Purification Results

99.80%
Purity
80.02%
Recovery
0.20%
Max Single Impurity

Comparative Analysis

The Sunpure-BS series demonstrates excellent performance for different oligopeptides:

Parameter Oligopeptide-5 (C18 Pro) Oligopeptide-10 (AQ C18)
Particle Size 8µm 10µm
Pore Size 120Å 100Å
Purity 99.00% 99.80%
Recovery 90.02% 80.02%
Loading Capacity 1% 3%

Sunpure-BS C18 Pro Highlights

  • Exceptional 90.02% recovery for Oligopeptide-5
  • 8µm particles for high resolution
  • 120Å pores ideal for medium-sized oligopeptides
  • Consistent 99% purity

Sunpure-BS AQ C18 Highlights

  • Superior 99.8% purity for Oligopeptide-10
  • Higher 3% loading capacity
  • 10µm particles with 100Å pores for larger oligopeptides
  • Maintained 80% recovery at higher loading

Technical Note: The Sunpure-BS series demonstrates versatility across different oligopeptide purification needs. The C18 Pro shows excellent recovery for medium peptides, while the AQ C18 achieves higher purity for larger peptides with increased loading capacity. Both maintain 3mL/min flow rates for efficient processing.

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